Introduction:
Norsteroids, including norandrostenedione and norandrostenediol, have garnered interest for their potential to enhance strength and body composition in resistance-trained individuals. This study investigates the effects of a specific dosage of norsteroid supplementation on body composition and strength in resistance-trained men.
Methods:
Ten resistance-trained men were enrolled in this study and divided into two groups: the norsteroid supplementation group and the placebo group. The norsteroid group received a daily dose of 344 mg, containing 224 mg of 19-nor-4-androstene-3,17-dione and 120 mg of 19-nor-4-androstene-3,17-diol. The placebo group received an identical-looking placebo. The supplementation lasted for 8 weeks, during which participants engaged in resistance training approximately 4 days per week.
Results:
The study’s results revealed no significant changes in body composition or strength for either group after the 8-week period. Both the norsteroid supplementation group and the placebo group exhibited no substantial alterations in strength, assessed using one-repetition maximum bench press and one-repetition maximum biceps curl, or in body composition, as determined by dual-energy x-ray absorptiometry.
Conclusions:
In this study involving a limited sample of resistance-trained men, supplementation with 344 mg/d of norsteroids (19-nor-4-androstene-3,17-dione and 19-nor-4-androstene-3,17-diol) showed no discernible effect on strength or body composition. Further research with a larger sample size and varying dosages may be necessary to comprehensively understand the impact of norsteroid supplementation on resistance-trained individuals.